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Nrf2 is a cytoprotective transcription factor that regulates the expression of a wide range of genes involved in detoxification, inflammatory, immune and antiviral responses (58)

A balanced diet combined with healthy lifestyle habits may help maintain optimal glutathione levels

The polysaccharides not only serve as carriers but also act as effectors to improve the TME, enhance immune functions, and produce synergistic effects with chemotherapy drugs

extract followed by exposure to gamma rays

Our bodies' glutathione levels decrease with age, stress, and exposure to toxins

Experiments could be designed to specifically assess compensation: a recent study using an action selection task, showed increased selection-related activation of parietal-premotor cortex in PD with milder clinical phenotype compared to both controls (suggesting upregulation of normal activity) and to PD patients with worse motor disease (suggesting that increased activity in these regions may be related to milder motor symptoms) 155