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The evolution of metazoan TrxRs from Gsr involved acquisition of a carboxy (C)-terminal extension to the enzyme that encodes the active site responsible for reducing Trx-disulfides [48, 51, 54]

Once it's denatured, it's not coming back

[DOI] [PubMed] [Google Scholar] 89.Gomez-Pinilla F

Scientific studies have shown that when glutamateinduced excitotoxicity occurs, it can cause damage to the structure and function of mitochondria
