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10.1002/jcp.30189 72 WangD.BieL.SuY.XuH.ZhangF.SuY.et al (2018)

2 Disease diagnosis As a diagnostic specimen, MB offers multiple advantages, including ease of sampling, noninvasiveness, self-collection capability, periodic availability, and fewer ethical concerns (Wong et al., 2018)

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Melatonin's role beyond sleep regulation Beyond its role in regulating seasonal physiology and influencing the circadian system and sleep patterns, melatonin is involved in cell protection, neuroprotection and the reproductive system [1]

One theory is that estrogen blocks the anion exchange transporter (see above) in the kidney, causing more uric acid to be excreted in the urine, and thus lowering the level of uric acid in the blood