ionization of glutathione The multiple dissociation constants disulfide: interpreting experimental pH-titration curves with ab initio MD simulations Study on Chemical Modifications of
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Journal of Clinical Oncology 42:205, 2024

Liou GY, Dppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P

In vitro evidence that a failure to partially degrade R protein is responsible for cobalamin malabsorption in pancreatic insufficiency

They performed the same ITC tests using PEI 25 kDa instead of 600 Da PEI

Safety is also a concern

4b and Extended Data Fig
