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CRT increased cortical density by 3.18 (0.05,6.31) gcm 2 (p = 0.05) but reduced cortical thickness by 0.07 ( 0.13, 0.01) mm (p = 0.03) relative to CON in (Fig

Eur J Vasc Endovasc Surg

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The removal of this region and the multivalent presentation on a ferritin nanoparticle significantly improved DCFHPs neutralizing potency in mice relative to the use of unedited spike, since it allows the immune system to not get distracted by creating an antibody response against a region that is ultimately nonneutralizing [134]

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Curcumin, a natural polyphenolic metabolites, has been shown in a systematic review of the literature to significantly reduce oxidative stress and exhibit antioxidant effects through multiple biological pathways, including inhibition of reactive oxygen species generation, upregulation of antioxidant enzyme expression, and regulation of lipid metabolism-related gene expression