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mild hypotension and dizziness reported infrequently PT-141 Side Effects# PT-141's side effects are systemic, reflecting its central mechanism: Nausea the most significant adverse event, reported in approximately 40% of women in RECONNECT trials and approximately 18% in male studies

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Interestingly, authors believed that Val66Met did not affect BDNF signaling but impaired cellular distribution and dysregulation of BDNF [56, 57]

Elevated levels, especially in conjunction with elevated BUN, suggest kidney dysfunction