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Preclinical research suggests TIMP-1 is implicated in fear and memory processes (80), and has shown to have a protective role in neurodegenerative disorder (81)

Systemic PPMO-mediated dystrophin expression in the Dup2 mouse model of duchenne muscular dystrophy

In this context, the modulation of glutamine on relevant signaling pathways as nuclear factor kappa B (NF-kB), mitogen-activated protein kinases (MAPKs), and heat shock protein and the influence of this amino acid on cell migration and adhesion molecules are highlighted