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If not repaired, these oxidative lesions to DNA would interrupt the sequence of events involved in the propagation of epigenetic signals, thus leading to dysregulation of transcriptional activity
They also point the way to a new class of antidepressants that could be freer of side effects and faster-acting than those in use today, and that may help patients for whom existing treatments dont work or have stopped working

Some individuals may experience mild gastrointestinal discomfort or injection-site irritation depending on dosage and administration method

doi: 10.1001/jama.2022.18931 2 OMahoneyLLRoutenAGilliesCEkezieWWelfordAZhangAet al