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Products containing bitter melon, cinnamon, fenugreek, or other herbs that may affect glucose metabolism or gastric motility should be discussed with the prescribing provider, as additive effects with tirzepatide are possible

Skin RNA sequencing of patients with severe pruritus in PN revealed robust upregulation of Th22-related genes and signaling pathways, including IL-22, IL-22 receptors (IL22RA1 and IL22RA2), and IL-22-associated cytokines
