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In November 2024, COFEPRIS approved Mounjaro (tirzepatide) for the treatment of type 2 diabetes in Mexico

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Late-passage or senescent ECs are more spread out and have decreased proliferative and angiogenic behaviors, with an increased chance to become apoptotic (78, 79)

Trial SURPASS-5 (JAMA 2022) Population 475 adults with T2D + insulin glargine

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[DOI] [PMC free article] [PubMed] [Google Scholar] 912
