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On the other hand, of the downregulated 323 probes, genes involved in cell cycle, nucleotide binding and to intracellular non-membrane-bounded organelles were particularly downregulated by shPttg2 treatment

Among them, NAC and Glutathione stand out for their powerful, overlapping roles

PLoS One 7 , e49452 (2012)

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Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)

The count data were filtered to remove genes with low expression, transformed using the variance stabilizing transformation from the DESeq2 package (51), and then batch corrected using ComBat (52)