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In healthy young adults aged 2040 years, administration of a single dose of carglumic acid 50 mg/kg augmented ureagenesis, as measured by the in vivo synthesis of radiolabeled urea during an intravenous infusion of radiolabeled sodium bicarbonate [2]

Metabolism of BA in both the healthy and CPSS dog populations was comparable to human metabolism 9

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Contradictory, a 10-day methamphetamine exposure caused prominent changes in circadian clock gene expression in only female rats, upregulating Per2 and Per3 while downregulating BMal1 , Npas2 and Clock genes

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In contrast, it is widely expressed in cancers, even in tissues which CT2 is not ordinarily present