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Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells

By contrast, in the GSH-C4-first sequence (Figure 3B), HA + GSH-C4 elicited a reproducible cytokine activation profile: at V3, levels of IFN-2 (p = 0.044), IFN- (p = 0.023), TNF- (p = 0.039), IL-6 (p = 0.044), IL-12p70 (p = 0.015), IL-23 (p = 0.034), and the epithelial alarmin IL-33 (p = 0.023) were significantly elevated versus baseline, whereas IL-1, MCP-1, IL-8, IL-10, and IL-18 remained unchanged

Additionally, Cao et al

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

10.1016/j.brainres.2013.01.007 58 KimY.-M.KimS.-J.TatsunamiR.YamamuraH.FukaiT.Ushio-FukaiM

Does a ketogenic diet as an adjuvant therapy for drug treatment enhance chemotherapy sensitivity and reduce target lesions in patients with locally recurrent or metastatic Her-2-negative breast cancer