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L-Carnitine plays a vital role in fatty acid metabolism, transporting fatty acids into the mitochondria to be converted into energy and again a deficiency can lead to reduce energy production

Levels of homocysteine may be increased by dietary habits, prescription medicines, or enzymatic mutations affecting homocysteine metabolism.43The results of meta-analyses confirm total homocysteine to be an independent risk factor for RVO.21,44Loewenstein et al.45 investigated the prevalence of genetic mutation in the enzyme methylentetrahydrofolate reductase (MTHFR) whose impaired activity may lead to hyperhomocysteinemia

Craig LB, Brush RS, Sullivan MT, Zavy MT, Agbaga MP, Anderson RE

Acetate metabolism in physiology, cancer, and beyond

Furthermore, leptin potentiates hepatic inflammation through TNF- release from Kupffer cells and stimulates CCL2 production in HSCs [227]

It is given to anyone with a specific vitamin deficiency