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Some studies indicate that HLA-Cw6 in patients with psoriasis may be associated with better biologic treatment efficacy, particularly with IL-23 and IL-17 inhibitors (207)

The formation of homo- or heterodimers is induced by the binding of ligands, which triggers the autophosphorylation of cytoplasmic tyrosine residues [9]
Meanwhile, HDAC7 cooperated with the E2 SUMO ligase, Ubc9, was also found to facilitate promyelocytic leukemia protein (PML) sumoylation and the formation of PML nuclear bodies [82], suggesting the SUMO-like function of HDAC7

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Zhou Z, Yu X, Tian E et al (2026) Aerobic exercise promotes hippocampal neurogenesis and ameliorates cognitive dysfunction induced by unilateral labyrinthectomy