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If it lasts more than a week or is severe, inform your doctor

[DOI] [PubMed] [Google Scholar] 84.Marcuard S.P., Sinar D.R., Swanson M.S., Silverman J.F., Levine J.S

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More critically, copper ions can catalyze vitamin C oxidation, rapidly breaking down the antioxidant and potentially creating irritating byproducts

[4] When treating severe megaloblastic anaemia, monitoring of potassium levels may be necessary as rapid cell production can cause hypokalaemia

doi: 10.1056/NEJMoa0810780