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Storage matters more here than it does for a robust small molecule, because peptides are fragile: heat, light, agitation and freeze-thaw cycles all degrade them, and a degraded peptide simply under-delivers with no visible warning

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Hepatic vagal efferents releasing ACh also exert a permissive effect on insulin action, increasing hepatocellular glucokinase activity and thereby potentiating glucose uptake (Hampson and Agius 2007) (Figure 5)

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