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The mechanisms underlying the association between adolescent cannabis use and risk of psychotic and cognitive symptoms later in life have been explored in various animal models using exposure to escalating doses of -9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis

There were 16 different (likely) pathogenic variants identified of which 11 have not been reported previously (depicted in light grey)

This creates an indirect but potentially meaningful therapeutic effect

However, further research is necessary to confirm any link

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Research on Depression and Mitochondrial Function In hypoxic research settings, DSIP has been observed to potentially preserve mitochondrial function and influence serotonin regulation