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Role of the unfolded protein response (UPR) in cataract formation

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Tambay, V., Raymond, V

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Biophys Biochem Res Commun 2005;338:55867

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Research published in the Journal of Gerontology by Grove and Kligman found that stratum corneum transit time was approximately 20 days in young adults but lengthened by more than 10 days in older adults (PMID: 6827031)

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Based on these findings, we propose that irisin exerts neuroprotective effects by attenuating the secretion of inflammatory mediators and reactive oxygen species by microglia

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This review provides an insight into the current knowledge of the AD, highlighting the need for an effective drug delivery to the brain

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