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Both were published in the New England Journal of Medicine in mid-2025

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The condition is unilateral in 97% of cases and accounts for about 10% of cases in which the testis is absent from the scrotum or inguinal canal [31]

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Another recently discovered mechanism by which proteins and particulates and possibly bacteria can penetrate the mucosa is via GAPs, in which large solutes such as 10 kDa dextran and proteins such as albumin traverse the mucosa where they are presented to subepithelial dendritic cells [19, 53, 62]

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