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In acute and severe cases, the combination of drugs is often used clinically to promote a synergistic effect and relief (Table 9)

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the combination of PLC, niacin and l-ARG was demonstrated to significantly improve total and single items of IIEF-6 [15], whereas combined PLC and acetyl-L-carnitine (ALC) was demonstrated to significantly improve penile erectile function together with mood, being more effective than testosterone, in particular, in improving IIEF-6 score and nocturnal penile tumescence in aging men with clinical symptoms of androgen decline [24]

Balance of brain oxytocin and vasopressin: Implications for anxiety, depression, and social behaviors