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Since cross-reactivity, including bronchospasm, between aspirin and other nonsteroidal anti-inflammatory drugs has been reported in such aspirin-sensitive patients, diclofenac sodium extended-release tablets should not be administered to patients with this form of aspirin sensitivity and should be used with caution in all patients with preexisting asthma

This finding established that the biological activity relevant to repair processes was largely captured within the shorter synthetic fragment

Lau DCW, et al

Labs can support broad review but may not capture local tissue or gut response

It's a difficult, often moving-target objective