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Acute systemic LPS injections induce pronounced but reversible changes in astrocyte gene expression in the prefrontal cortex, along with an approximate 25% decrease in astrocyte branch and process volumes, but with few currently detectable changes in astrocyte physiology and basic preservation of astrocyte core homoeostatic functions such a potassium buffering

USA 99 , 1688116886, (2002)

PMT-O9-1A substantially mitigated PD-L1 expression and improved its treatment efficacy through both external PD-L1 blockade and internal PD-L1 degradation mechanisms in lung cancer