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Lancet Respir
M.JiangC.HatchA
Todd Schlesinger, MD
It has been shown that 1,25(OH) 2 D 3 suppress the differentiation of Th1 cells, which are usually involved in exacerbated immune responses against TB disease, and it favors the differentiation of anti-inflammatory regulatory T cells
Nevertheless, in animals subjected to CSD and received ALA administration, the levels of all above signaling proteins were noticeably reduced to near the control values (Figure 5A)
This drives massive proton influx into the endosomal compartment
