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FEBS J 288(23):68156827

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For example, hyaluronic acid (HA) modified pH-sensitive lipid polymer hybrid nanoparticles (LPH NPs) co-deliver erlotinib (ERL) and bevacizumab (BEV), forming HA-ERL/BEV-LPH NPs that exhibit high tumor tissue accumulation and low systemic toxicity

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27 Besides, nanostructures are always employed to sustain the release of encapsulated compounds in order to reduce dose and dosing frequency, thereby increasing patient compliance and minimizing side effects