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Why this is the case remains unclear

Age-Related Decline and the Anti-Aging Question The 60% decline in plasma GHK-Cu from age 20 to 60 has prompted speculation that GHK-Cu supplementation could slow or partially reverse aspects of biological aging

Niculescu AB III, Chen X, Smeets M, Hengst L, Prives C, Reed SI

Post-translational regulation of p53 The p53 protein undergoes post-translational modifications (PTMs) at its five discrete domains, namely transactivation domains (TADs), proline-rich domain (PRD), DBD, the tetramerization domain (TD), and carboxy-terminal domain (CTD)

Hao L, Nie YH, Chen CY, Li XY, Kaliannan K, Kang JX