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This parental line, which intrinsically expresses minimal CFTR protein, serves as a reliable model and is frequently used as a null-background for the stable overexpression of wild-type, F508del, or other CFTR variants, enabling the study of their function and response to modulators (Ousingsawat et al., 2011

PMID: 22113581 42

Kandemir FM, Caglayan C, Aksu EH et al (2020) Protective effect of rutin on mercuric chloride-induced reproductive damage in male rats

doi: 10.1016/j.ejpb.2022.08.021 [DOI] [PubMed] [Google Scholar] 61.Fu F, Wang W, Wu L, et al

Researchers and practitioners working in compounding contexts should consult current FDA guidance for the most up-to-date compounding status, as this is distinct from research-use regulations