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Changing GPX4 levels did not protect cells from death stimuli acting outside the ferroptosis pathway, proving that GPX4 control is confined to ferroptosis alone

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For MAPK pathways, KPV inhibits all three subfamilies: ERK1/2 (extracellular signal-regulated kinases) JNK (c-Jun N-terminal kinases) p38 MAPK Phosphorylation of these kinasesrequired for activationdrops markedly in cells exposed to KPV

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