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Link Devaraja, S., et al

The vulnerable versatility of Salmonella antibiotic persisters during infection

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It showed that applying 10% bacterial extract to sensitive, reactive skin helped with better barrier function and decreased skin sensitivity

The activation phase is initiated by danger signals (e.g., ROS (O 2 - , H 2 O 2 ), lysosomal rupture, or K + efflux), leading to NLRP3 oligomerization, recruitment of the adaptor protein apoptosis-associated speck-like protein containing a CARD (ASC), and activation of pro-caspase-1 [41]