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It also impairs base and nucleotide excision repair pathways and causes widespread epigenetic dysregulation, such as aberrant DNA methylation and histone modification, that silence tumor suppressor genes [176]

Journal of the American Geriatrics Society 60 (6): 10571063

Also, all the cases described here cover a pre-IDP period

Metabolic control of longevity
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Cytoprotection BPC-157 has protective effects on endothelial cells, neurons, and myocytes
