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Description
In patients with T2DM and other metabolic abnormalities, elevated SELENOP levels exacerbate IR and reduce the efficiency of insulin transport into the CNS, thereby compounding metabolic dysfunction and possibly contributing to neurodegenerative processes [224]

Oxidative stress, one of the main causes of immune dysfunction and a common stressor in poultry, arises from an imbalance between the rate of ROS production and accumulation in cells and interstitial tissues and its detoxification and clearance by the bodys available antioxidants

Steady state of body systems that living organisms maintain

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This integral association between oxidative stress and a proinflammatory state may affect cellular redox equilibrium, thereby imposing a direct role in modulating the pattern of gene expression in lung tissues

Second, the molecular pathways found from the literature review provided the basis to develop a systems architecture, for oxidative stress
