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Here, we present a statistically optimized culture protocol that suppresses fibroblast activation while preserving cell viability under standard culture conditions

Function: It increases GH and insulin-like growth factor 1 (IGF-1) production without raising prolactin levels significantly

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An association is established between oxidative stress conditions and the augmentation of an inflammatory state in pathophysiology, regulated by the oxygen- and redox-sensitive pleiotropic cytokines.