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Thus, these findings suggest that genistein (and possibly other Nrf-activating agents) coordinately upregulate both the cosubstrate (GSH) and enzyme (GPx-1 or GPx-2) necessary for hydrogen peroxide reduction, thereby contributing to the overall antioxidant capacity of the cell

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However, if you have a sensitive stomach, taking it with a small snack is perfectly acceptable

What is the optimal administration method for vitamin B12 supplements