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The extracellular L-cysteine/L-cystine redox balance, and thus the synthesis of GSH, is finely regulated by the intracellular conversion of L-cystine into L-cysteine (10), and its impairment is related to oxidative stress and other pathological disorders

The shift to the no-Cys diet immediately triggered weight loss in the Cse / mice, with a 10% decrease over 3 days, compared with a 0% change for Cse +/ mice (Fig

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