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10.1007/s00204-016-1692-0 Arch

[DOI] [Google Scholar] 310.Hwang M., Kwon M., Kim B

Importantly, cellular fractionation revealed that Hs PEX39 loss led to an accumulation of precursor PHYH in the cytosolic fraction and a decrease of mature PHYH in the organellar fraction, thus demonstrating impaired import of PTS2-containing proteins (Extended Data Fig

Although the exact mechanisms of HPH are not fully understood, international guidelines recognize chronic hypoxia as a primary trigger

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Glutathione also plays a vital role in regenerating another important antioxidant, vitamin C, thus amplifying its health benefits