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Description
Early, small trials suggested a beneficial effect of ALCAR with respect to cognitive decline (98-100), whereas later, larger trials found little-to-no effect compared to placebo (101-103)

Best Form: Acetyl-L-carnitine is often suggested as a better option than L-carnitine due to its excellent absorption and potential brain health benefits

On the outer mitochondrial membrane, CPTI (carnitine-palmitoyl transferase I) catalyzes the transfer of medium/long-chain fatty acids esterified to coenzyme A (CoA) to L-carnitine

doi: 10.1196/annals.1320.018
A randomized controlled trial

Patients with cirrhosis have an acquired L-carnitine deficiency [12] and levels of free fatty acids progressively elevate with the severity of liver cirrhosis [78]
