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Maharajan N, Cho GW, Jang CH

mTOR is an intracellular energy sensor [35, 36] and its activity is regulated by nutrients, energy supply, and various hormones [37, 38]

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calculated as the sum of reduced GSH and two times the amount of oxidized glutathione (GSH + 2 GSSG)) levels in the serum and in the tumour interstitial fluid (TIF), the extracellular compartment surrounding tumours