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Methylsulfonylmethane (MSM) is an organic, white crystalline substance that contains 34% sulfur

particularly inclusion of "among others"... Response: We have replaced this sentence with: While these three components are all directly related to ghrelin, one cannot deny the complex interrelationships between ghrelin and the multitude of other systems beyond simply the typical feeding circuitry of this peptide. Line 365-6: Statement "In addition to this, similar situations that lead to drug relapse also lead to relapse in dieting individuals (Nair et al., 2011)" is confusing

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10.1016/j.tips.2014.04.007 186 WalwynW.EvansC

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