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Glutathione has been shown to protect B12 from degradation by pollutants, increasing its availability for the continuation of the methylation reaction (Watson)
All other amino acidderived hormones are water soluble
Vitamin C, the other antioxidant often shelved in the same vitamins and injectables category, is oxidation-sensitive for the same underlying reason, which is why both are handled with an eye on air and light
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