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Using redox cycling quinones to increase production of hydrogen peroxide and by measuring transcription by nuclear run-on analysis, it was then shown that a sustained increase the amount of GSH in cells could be achieved by increasing the transcription of GCLC (Shi et al., 1994

For more detailed information on deficiencies common in autism spectrum disorders, searching for "common deficiencies in autism" will provide additional resources and studies

Interestingly, BSO alone was insufficient to induce ferroptosis in MDA-MB-231 cells (Supplementary Fig

The liver relies on glutathione for detoxification reactions and for buffering oxidative byproducts created during normal metabolism

SOD and catalase mimetic compounds naturally exhibit several orders of magnitude lower rate constants than their corresponding enzymes, however, their use in extracellular environments, where concentrations of enzymes are rather low, is of significant importance

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