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Animal studies demonstrate that severe vitamin A deficiency or excess during critical periods of development results in a spectrum of malformations, especially affecting craniofacial structures, limbs, and visceral organs (65)

AguilarECLeonelAJTeixeiraLGSilvaARSilvaJFPelaezJMet al

Arch Intern Med 170(3):256261

Leibetseder (1995) pointed out that EP, FI or BW during the early laying period were not significantly affected by the supplementation of a laying hen's diet with either 500 mg L-carnitine or nicotinic acid, or a combination of the two substances

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[17] Demarquoy C, Demarquoy J