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Increased sympathetic drive has been implicated in increased blood pressure variability with repetitive sympathetic activation and blood pressure surges impairing baroreflex and cardiovascular reflex functions 259

Comorbidities and metabolic derangement of NAFLD

However, although they measured TPO antibodies before IFN treatment of HCV, they did not remeasure levels after treatment

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Adjobo-Hermans et al., 2008, 2013
Further, our analyses revealed that the multi-omics signature associated with higher circulating TMAO concentrations and, therefore, elevated cardiovascular risk, shifted from obesity with increased insulin resistance toward overt T2D and IHD with only three variables (age, eGFR, and serum butyryl-carnitine) consistently being strong contributors across models built with the BMIS, T2D and IHD disease groups