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Apart from the potential of taurine to regulate cell volume (23), its osmolytic activity can also contribute to protein folding in the endoplasmic reticulum (ER) (24)

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In monocytes and macrophages, caspase-1 activates caspases-3/7 and induces apoptosis in the absence of GSDMD while caspases-3/7 specifically block pyroptosis by cleaving GSDMD during apoptosis, which is called bidirectional crosstalk [169]

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Mutations in KRAS lead to the upregulation of the expression of the SLC7A5, SLC38A2, and SLC25A22 transporters in cancer cells, thereby promoting glutamine uptake [50]

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