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p53 inhibits the transcription of SLC7A11 by directly binding to its promoter in fibroblasts and certain cancer cells, which then affects the GPX4-regulated classical pathway and ultimately leads to ferroptosis (Fig
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Witschi A, Reddy S, Stofer B, Lauterburg BH (1992)
Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species
10.3390/toxins10050202 114
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