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As an example, we have previously shown that adenovirus-mediated induction in human adult OLs of low levels of p53, a transcription factor that regulates apoptosis and can be detected in OLs in actively demyelinating MS lesions, renders these cells susceptible to subsequent FasL- and TRAIL-medicated killing 45

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[DOI] [PubMed] [Google Scholar] 33.Zhu H.T., Bian C., Yuan J.C., Chu W.H., Xiang X., Chen F., Wang C.S., Feng H., Lin J.K
