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Proliferating HBs expand the liver bud based on cues from HGF, FGF, Wnt signaling, and Hippo signaling (Macchi and Sadler, 2020)

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The treatments included PBS, oridonin, orid-liposome, and TLR2 pep-orid-liposome, each administered intravenously at a dose of 5 mg/kg body weight

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The medication should be discontinued at least 2 months before planned pregnancy due to long half-life
