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Dimethyloxallyl glycine-loaded mesoporous bioactive glass/poly(D,L-lactide) composite scaffolds with ultrasound stimulation for promoting bone repair

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The cumulative mortality was observed for 21 days and the relative percent survival (RPS) was calculated

141,142 Recurrent somatic mutation of residues are mainly located at enzymatic active sites that bind to isocitrate, typically at R132 including R132H, R132L, R132S, R132C, and R132G in IDH1, and R140Q or R172K in IDH2

103 Activation of histone deacetylase Sirtuin1 (SIRT1) promotes ferroptosis in HNC cells, increases ZEB1 expression, and decreases E-cadherin levels

This causes the release of cyt c into the cell cytoplasm, which then activates a caspase cascade, particularly caspase-3 and caspase-9, resulting in mitochondrial impairment and triggering apoptosis (Yao et al., 2021)