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Garrido-Gil P, et al
E.McGuireM
doi:10.1093/jn/133.11.3972S
These data indicate that decrements in IGF-I and IGFBP-5 levels in the skeletal muscles of Class II heart failure patients play critical roles in MHC isoform distribution, which switch to more glycolytic properties, evidenced by a significant increase in hybrid isoforms and in particular the MHC IIa/IIx isoforms
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