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It depends on the need

People on certain medications can be deficient in B12 if the medicine blocks the bodies ability to absorb B12 (for example the Birth control pill, proton pump inhibitors, and Metformin )

doi: 10.1134/S0006297911110022

Both types of Vitamin B12 are important for keeping your nerves healthy and your energy up

Acute consumption of organic and conventional tropical grape juices (Vitis labrusca L.) increases antioxidants in plasma and erythrocytes, but not glucose and uric acid levels, in healthy individuals
Finally we can also reduce 5-alpha reductase activity by decreasing total androgen production
