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Although the exact cause and mechanism of both types of IBD are yet to be completely understood, environmental or autoimmune-related factors are major causative factors 90,91

ADDF: Alzheimers Drug Discovery Foundation

Platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-), tumor necrosis factor-beta (TNF-), and thrombin also activate NOX in vascular smooth muscle cells (VSMC)

van der Weijden CWJ, Biondetti E, Gutmann IW et al (2023) Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status

Erdman J, Oria M, Pillsbury L, editors
